Research – Progesterone

Serving Women of Planet Earth...

Differentiating Between Natural Progesterone and Synthetic Progestins: Why Important link² link ³ link⁴
Progesterone Supports a Healthy Heart link⁵
Progesterone supports the brain to heal from damage after traumatic brain injury (the Human Brain Has an Inordinately Large Number of Progesterone Receptor Sites) link ⁶ link⁷ link⁸ link⁹
Progesterone is the precursor for Allopregnanalone (the nervous system has the capacity to bio-convert progesterone into its active metabolite allopregnanolone. The enzymes required for progesterone and allopregnanolone synthesis are widely distributed in brain and spinal cord. Increased local biosynthesis of pregnenolone, progesterone and 5α-dihydroprogesterone may be a part of an endogenous neuroprotective mechanism in response to nervous system injuries. Progesterone and allopregnanolone neuroprotective effects have been widely recognized) link¹⁰
“Progesterone prevented membrane cell damage, motoneuron loss and cell death. Allopregnanolone treatment was also neuroprotective.” link¹¹
Progesterone supports the body to normalize the symptoms of Multiple Sclerosis link¹²

Progesterone Supports a Happy Mood, via Allopregnanolone Production link¹³
Progesterone Supports a Healthy Heart link ¹⁴ llink¹⁵
Facilitates thyroid hormone function and utilization
“Estrogen dominance causes the liver to produce high levels of a protein called “thyroid binding globulin”, which, as its name suggests, binds the thyroid hormone and decreases the amount of thyroid hormone that can be assimilated into and utilized by the cells.What does this lead to? Low thyroid function and all of the negative side effects that come along with it.” link¹⁶link¹⁷link ¹⁸ link¹⁹
Progesterone is Anti-estrogenic (the average 54 year old male in the US, has higher estrogen levels that the average 54 year old female!) link²⁰
Progesterone Supports Normal, Programmed Cell Replacement in breast, ovarian & prostate tissues link²¹link²² link²³ link ²⁴
Progesterone Supports the Body’s Natural Process of Inhibiting Tumor Formation in Breast & Prostate Cells link²⁵²⁶

Progesterone receptor modulates estrogen receptor-α action in breast cancer link²⁸ link²⁹ link³⁰
Progesterone Supports the Body’s Ability to Alleviate the underlying cause of Hot Flashes link³¹ link ³²
Progesterone Supports the Activity of Osteoblast Cells (in US, women, on average, lose 1.5% bone/year) (bone health) “Progesterone plus estradiol or other anti-resorptive therapies adds 0.68%/year and may be a highly effective osteoporosis treatment. US average is 1.5% bone loss/year” link³³
Progesterone as a Bone-Trophic Hormone link³⁴ link³⁵
Progesterone Supports Phase IV sleep (the restorative, restful sleep) link³⁶ link³⁷ link³⁸

Differentiating Between Natural Progesterone and Synthetic Progestins: Why Important link³⁹
Progesterone vs. synthetic progestins: a systematic review and meta-analysis (a study involving 86,881 postmenopausal women) link⁴⁰
Progesterone Supports Fertility, Conception, Full-Term Pregnancy link⁴¹ link⁴²link⁴³link⁴⁴
High Levels of Progesterone During Pregnancy link⁴⁵
Progesterone Supports the body’s ability to correct the underlying cause of most of the 150 different symptoms of PMS/PMDD link⁴⁶
Progesterone Facilitates thyroid hormone function and utilization
“Estrogen dominance causes the liver to produce high levels of a protein called “thyroid binding globulin”, which, as its name suggests, binds the thyroid hormone and decreases the amount of thyroid hormone that can be assimilated into and utilized by the cells.What does this lead to? Low thyroid function and all of the negative side effects that come along with it.” link⁴⁷link⁴⁸link ⁴⁹link ⁵⁰
Progesterone Supports a Woman’s Normal Libido (Progesterone is the Precursor for Testosterone,source of libido in women)link⁵¹ link⁵² link⁵³ link⁵⁴
Progesterone Supports Healthy, Happy Ovaries (lol) link⁵⁵ link⁵⁶ link ⁵⁷ link⁵⁸
Progesterone Supports Normal, Programmed Cell Replacement in breast & ovarian tissues link ⁵⁹ link⁶⁰link⁶¹ link ⁶² link⁶³

Progesterone Supports a Healthy Endometrium link⁶⁴ link ⁶⁵
Progesterone Supports Inhibition of Tumor Formation in Breast Cells link⁶⁶ link⁶⁷ link⁶⁸ link⁶⁹ link⁷⁰
Progesterone Supports women in Menopause link⁷¹
Progesterone Alleviates the underlying cause of Hot Flashes link⁷² link⁷³
Supports Osteoblast Function (bone health) “Progesterone plus estradiol or other anti-resorptive therapies adds 0.68%/year and may be a highly effective osteoporosis treatment. US average is 1.5% loss/year” link⁷⁴
Progesterone as a Bone-Trophic Hormone link⁷⁵ link⁷⁶
Progesterone Supports Phase IV sleep (the restorative, restful sleep) link⁷⁷ link ⁷⁸ link⁷⁹
Progesterone protects the brain from damage after traumatic brain injury link⁸⁰ link⁸¹
Progesterone is the Precursor to Allopregnanolone Supports a Happy Mood link ⁸²

Progesterone is the Precursor for Testosterone link⁸³ link⁸⁴
Testosterone Supports Improved Muscle Mass link⁸⁵
Testosterone Supports Weight Loss link⁸⁶
Testosterone Strengthens Bones link⁸⁷
Testosterone Supports a Healthy Heart link⁸⁸
Testosterone Fuels Libido link⁸⁹
Testosterone Supports an E.D.-Free Life! link⁹⁰ link ⁹¹ link ⁹² link ⁹³
Testosterone Supports a Decrease Alzheimer’s Risk & Improves Cognitive Function link ⁹⁴ link ⁹⁵

Testosterone Supports Increased Athletic Performance link ⁹⁶
Testosterone Supports Increased Hemoglobin (low hemoglobin=anemia) link ⁹⁷
Testosterone Supports Male Magnetism Toward Women link ⁹⁸
Progesterone Supports Normal Breast Size in Men (links coming soon)
Progesterone Blocks 5AR, the Enzyme that Converts a Man’s Valuable Testosterone to DHT (normal consequence of aging). DHT is Implicated in an Elevated PSA Count (links coming soon)
Progesterone Is a Proven, Successful Treatment for Traumatic Brain Injury (links coming soon)
The Human Brain Has an Inordinately Large Number of Progesterone Receptor Sites, Ergo, Progesterone Supports a Balanced Brain Chemistry (links coming soon)
Repeat: Progesterone is the Precursor for Testosterone link⁹⁹ link¹⁰⁰