Progesterone & HRT

Progesterone & HRT
March 25, 2018 Writing Department


HRT is an acronym for Hormone replacement therapy. This is the default treatment prescribed by most doctors when a woman enters menopause (menopause nromally occurs at the age of 50-51 or may be surgically induced at any younger age). HRT may contain estrogen and progestin (synthetic progesterone), however, normally contains synthetic estrogens. Administration methods are:

  • tablet
  • patch
  • suppository
  • vaginal cream

At menopauyse HRT was the default treatment choice, as it may alleviate some of the following symptoms:

  • hot flashes
  • night sweats
  • anxiety
  • sleep disorders
  • vaginal dryness

HRT is prescribed under the belief that a woman has reduced levels of estrogen at menopause. However, according to Dr. John Lee’s research, 75% of menopausal women make a sufficient amount of estrogen in their adrenal glands & fat cells

Is HRT Safe?

HRT as a default therapy changed dramatically in 2002, when a large clinical trial found that HRT posed more health risks than benefits for postmenopausal women. As the number of risk factors attributed to synthetic hormone therapy became universally accepted, doctors became less likely to prescribe it. Many women on hormone therapy discontinued its use, often without consulting their physicians.

What are the risks of hormone therapy?
(quoted from the Medline Database)


Doctors have long known that taking estrogen increases a person’s risk for blood clots. Generally, this risk is higher if you use birth control pills, which contain high doses of estrogen. Your risk is even higher if you smoke and take estrogen. The risk is not as high when estrogen skin patches (transdermal estrogen) are used.

Breast cancer :

Women who take estrogen therapy for a long period of time have a small increase in risk for breast cancer. Most guidelines currently consider hormone therapy safe for breast cancer risk when taken for up to 5 years. Endometrial/uterine cancer:The risk for endometrial cancer is more than five times higher in women who take estrogen therapy alone, compared with those who do not. However, taking progesterone with estrogen seems to protect against this cancer. Endometrial cancer does not develop in women who do not have a uterus.


Heart disease:Estrogen may increase the risk of heart disease in older women, or in women who began estrogen use more than 10 years after their last period. Estrogen is probably the safest when started in women under age 60, or within 10 years after the start of menopause. Deep venous thrombosis (DVT or blood clot in a vein) and pulmonary embolus (PE or blood clot in the lungs) are more common in women who take oral estrogen, regardless of their age.Stroke:

Women who take estrogen have an increased risk for stroke. Women who also smoke, have heart disease, or are at higher risk for heart disease and stroke are less likely to be given estrogen hormones.


Several studies have shown that women who take estrogen/progestin (synthetic progesterones) therapy have an increased risk for developing gallstones.”

Are There Safe Alternatives?

The hormones used in most HRT protocols are foreign to the female body and while they address some of the symptoms women struggle with at menopause, they do so with a price. Hormone replacement therapy can be accomplished successfully with hormones that are biologically identical to those made by the woman’s natural biological processes and therefore, work in harmony with your body’s natural systems.

Oral administration invites the liver to intercept those hormones, while a proper, plant-based cream method of administration bypasses the liver and delivers hormone “messengers” to the correct receptor sites where they are able to successfully carry out their mission. More detail can be accessed here: “Why is Cream Form Better?”

Achieving Optimal Health at Menopause
We live in a time of “better living through chemistry…” and for that reason it is a challenge to acquire and maintain optimal health and wellness.

Following are some well established guidelines for you to achieve that goal:

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