Endocrine-disrupting chemicals (EDCs) are the substances present in the environment, food, and consumer products that interfere with hormone biosynthesis, metabolism, or action altering the normal homeostatic balance of an organism. Various validation studies have contributed to the growing knowledge of different EDCs and their mechanism of action (Diamanti-Kandarakis et al. 2009). The previous known mechanism was that they exert their actions through nuclear hormone receptors, including Estrogen receptors (ERs), Androgen receptors (ARs), progesterone receptors, Thyroid receptors (TRs), and retinoid receptors, either acting as an agonist or as an antagonist (Diamanti-Kandarakis et al. 2009). However, present scientific research has elucidated the mechanisms that are broader compared to the previously established.