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Manic Depression


Depressive and manic depressive illness are the two major types of depressive illness, also known as affective disorders, or mood disorders, because they primarily affect a person's mood. Different terms, respectively, include unipolar and bipolar disorder. You may have heard of other forms of depressive illness such as dysthymia, a type of chronic moderate depression, or cyclothymia, a form of manic depression in which the cycles (mood swings) are not quite as severe. In this booklet, we will predominately discuss major depressive disorder and manic depression, which encompasses symptoms of depression and mania or hypomania, a more moderate syndrome than full-blown mania.

It is estimated that over 17.4 million adults in the U.S. suffer from an affective disorder each year--that's one out of every seven people. If you are not affected now, chances are that at some point in your life, you yourself or someone you know will become affected. If you are a woman, you are twice as likely as a man to experience major depression while manic depression occurs equally among the sexes. Although these illnesses can occur at any age, many have their onset within the 25-44 age range.

Where do these illnesses come from? Genetic, biochemical and environmental factors can each play a role in onset and progression. While we all experience occasional highs and lows, affective disorders are characterized by their extremes in intensity and duration. Even at their most intense, the symptoms are often mistaken for other medical problems or dismissed as a reflection of someone's personality, age, social influence or background.

Research indicates that only one third of those with major depression will get proper treatment, and two thirds of those with any kind of affective disorder who do receive treatment will be misdiagnosed. These statistics reflect the insidiousness of the illness and the importance of both public and physician education. A lag in diagnosis and treatment could prove deadly; people with severe, untreated depression have a suicide rate as high as 15 percent. In fact, the number one cause of suicide in the U.S. is untreated depression.

Don't be overwhelmed by these sobering statistics. Of all psychiatric illnesses, affective disorders are among the most responsive to treatment. If given proper care, approximately 80 percent of patients with major depression demonstrate significant improvement and lead productive lives. Although the treatment success rate is not as high for bipolar disorder, a substantial number experience a return to a higher quality of life.

It is crucial that you learn the symptoms and act early!

Symptoms of Depression

  • Prolonged sadness or unexplained crying spells

  • Significant changes in appetite and sleep patterns

  • Irritability, anger, worry, agitation, anxiety

  • Pessimism, indifference

  • Loss of energy, persistent lethargy

  • Feelings of guilt, worthlessness

  • Inability to concentrate, indecisiveness

  • Inability to take pleasure in former interests, social withdrawal

  • Unexplained aches and pains

  • Recurring thoughts of death or suicide


Symptoms of Mania

  • Heightened mood, exaggerated optimism and self confidence

  • Decreased need for sleep without experiencing fatigue

  • Grandiose delusions, inflated sense of self-importance

  • Excessive irritability, aggressive behavior

  • Increased physical and mental activity

  • Racing speech, flight of ideas, impulsiveness

  • Poor judgment, easily distracted

  • Reckless behavior such as spending sprees, rash business decisions, erratic driving, sexual indiscretions

  • In the most severe cases, hallucinations


Anyone experiencing four or more of the above symptoms of either or both depression or mania should seek help if symptoms persist for longer than two weeks.

The Cause of Affective Disorders: It's Not Just in Your Head

Research shows that some people may have a genetic predisposition to affective disorders. If someone in your family has had such an illness, that does not necessarily mean you will develop it, nor does it explain conclusively why you did. It does increase your chances of experiencing depression of an endogenous nature (biological in basis). This is commonly referred to as clinical depression to distinguish it from short-term states of depressed mood or unhappiness. Even if you don't have a genetic predisposition, your body chemistry can trigger the onset of a depressive disorder, due to the presence of another illness, altered health habits, substance abuse, or hormonal fluctuations.

Depression can also be triggered by distressing life events, resulting in reactive depression. Losses and repeated disillusionment, from death to disappointment in love, can cause anyone to feel depressed especially if they have not developed effective coping skills. If these symptoms persist for more than two weeks, maintaining or increasing in intensity, this reactive depression may actually have evolved into a clinical depression.

Regardless of its cause, the presence of depressive or manic depressive illness indicates an imbalance in the brain chemicals called neurotransmitters. In other words, the brain's electrical mood regulating system is not working as it should. Proper treatment will vastly improve your level of functioning and can usually restore you to your "old self." Many people require long-term, even life-long, maintenance treatment which significantly decreases the likelihood of recurrences.

Treatment for Depression

Successful treatment includes tissue cleansing, counseling, dietary, lifestyle modifications


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